Copper-catalyzed electrophilic amination of diorganozinc reagents

被引：245

作者：

Berman, AM ^{[1
]}

Johnson, JS ^{[1
]}

机构：

[1] Univ N Carolina, Dept Chem, Chapel Hill, NC 27599 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2004年 / 126卷 / 18期

关键词：

D O I：

10.1021/ja049474e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The copper-catalyzed electrophilic amination of diorganozinc reagents employing O-acyl N,N-dialkyl hydroxylamine derivatives as aminating agents is described. This reaction offers a general method for the preparation of tertiary amines in high yields and is noteworthy for its convenience both in terms of reaction conditions employed (room temperature, ≤1 h) and ease of product isolation (acid/base extractive workup). Copyright © 2003 American Chemical Society.

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页码：5680 / 5681

页数：2

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