In vivo transduction of an Stx-encoding phage in ruminants

被引：50

作者：

Cornick, Nancy A.

Helgerson, Amy F.

Mai, Volker

Ritchie, Jennifer M.

Acheson, David W. K.

机构：

[1] Iowa State Univ, Dept Vet Microbiol & Prevent Med, Ames, IA 50010 USA

[2] Univ Maryland, Sch Med, Dept Epidemiol & Prevent Med, Baltimore, MD 21201 USA

[3] Tufts Univ New England Med Ctr, Boston, MA 02111 USA

来源：

APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 2006年 / 72卷 / 07期

关键词：

D O I：

10.1128/AEM.00157-06

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 [微生物学]; 0836 [生物工程]; 090102 [作物遗传育种]; 100705 [微生物与生化药学];

摘要：

We assessed the ability of a kanamycin-marked Stx phage to move into a commensal, ovine Escherichia coli strain in the ruminant gastrointestinal tract. Transduction was detected in 19/24 sheep tested, resulting in the recovery of 47 transductants. Subtherapeutic doses of the quinolone antibiotic enrofloxacin did not increase the rate of transduction.

引用

页码：5086 / 5088

页数：3

共 16 条

[1]

Acheson DWK, 1998, INFECT IMMUN, V66, P4496

[2]

PREVALENCE AND SOME PROPERTIES OF VEROTOXIN (SHIGA-LIKE TOXIN)-PRODUCING ESCHERICHIA-COLI IN 7 DIFFERENT SPECIES OF HEALTHY DOMESTIC-ANIMALS [J].