Left Ventricular Rotational Mechanics in Acute Myocardial Infarction and in Chronic (Ischemic and Nonischemic) Heart Failure Patients

被引：62

作者：

Bertini, Matteo ^{[1
,2
]}

Nucifora, Gaetano ^{[1
]}

Marsan, Nina Ajmone ^{[1
]}

Delgado, Victoria ^{[1
]}

van Bommel, Rutger J. ^{[1
]}

Boriani, Giuseppe ^{[2
]}

Biffi, Mauro ^{[2
]}

Holman, Eduard R. ^{[1
]}

Van der Wall, Ernst E. ^{[1
]}

Schalij, Martin J. ^{[1
]}

Bax, Jeroen J. ^{[1
]}

机构：

[1] Leiden Univ, Med Ctr, Dept Cardiol, Leiden, Netherlands

[2] Univ Bologna, Dept Cardiol, Bologna, Italy

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2009年 / 103卷 / 11期

关键词：

SPECKLE TRACKING ECHOCARDIOGRAPHY; SYSTOLIC TORSION; DILATED CARDIOMYOPATHY; 2-DIMENSIONAL STRAIN; STANDARDS COMMITTEE; OF-ECHOCARDIOGRAPHY; RECOMMENDATIONS; QUANTIFICATION; DYSFUNCTION; INDEX;

D O I：

10.1016/j.amjcard.2009.02.010

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Left ventricular (LV) twist and untwisting rate are emerging as global and thorough parameters for assessment of LV function. This study explored differences of LV twist and untwisting rate in patients with acute myocardial infarction (AMI) and patients with ischemic and nonischemic chronic heart failure (HF). Fifty patients with AMI, 49 with ischemic HF, and 38 with nonischemic HF were studied. As a control group, 28 subjects without evidence of structural heart disease were included. Speckle-tracking analysis was applied to LV short-axis images at basal and apical levels. LV twist was defined as the net difference of apical and basal rotations at isochronal time points. The first time derivative of LV untwist was defined as the LV untwisting rate. Compared with control subjects, peak LV twist was decreased in patients with AMI and extremely decreased in those with HF (p <0.001, analysis of variance). A strong correlation (r = 0.87, p <0.001) was found between peak LV twist and LV ejection fraction in the overall study population. LV untwisting rate was progressively decreased in patients with AMI and HF compared with control subjects (p <0.001, analysis of variance). A moderate correlation (r = 0.56, p <0.001) was noted between peak LV untwisting rate and grade of diastolic dysfunction in the overall study population. In conclusion, LV twist and untwisting rate are strongly related to LV systolic and diastolic functions, respectively. Impairment of LV function observed in patients with AMI and HF is associated with a decrease of LV twist and untwisting rate. (C) 2009 Elsevier Inc. All rights reserved. (Am J Cardiol 2009;103:1506-1512)

引用

页码：1506 / 1512

页数：7

共 25 条

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