Kidney development: from ureteric bud formation to branching morphogenesis

被引：67

作者：

Michos, Odysse ^{[1
]}

机构：

[1] Columbia Univ, Med Ctr, Dept Genet & Dev, New York, NY 10032 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 2009年 / 19卷 / 05期

关键词：

MICE LACKING GDNF; GROWTH FACTOR/SCATTER FACTOR; ENTERIC NERVOUS-SYSTEM; URINARY-TRACT; METANEPHRIC KIDNEY; DUCT EPITHELIUM; NEPHRON NUMBER; MET RECEPTOR; MOUSE; ORGANOGENESIS;

D O I：

10.1016/j.gde.2009.09.003

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Epithelial branching morphogenesis is critical to the formation of various organs such as the vasculature, mammary glands, lungs, and kidneys in vertebrate embryos. One fascinating aspect of branching morphogenesis is to understand how a simple epithelial tube grows by reiterative branching to form a complex epithelial tree structure. Recent studies combining mouse genetics and chimeric analysis with live imaging have uncovered the molecular networks and interactions that govern kidney branching morphogenesis. This review focuses on ureteric bud (UB) formation and epithelial branching during kidney development. The invasion of the metanephric mesenchyme by the UB is a fundamental step toward establishing the cyto-architecture of the kidney and determining the number of nephrons, which form the filtration units of the adult kidney.

引用

页码：484 / 490

页数：7

共 52 条

[1] Branching morphogenesis of the ureteric epithelium during kidney development is coordinated by the opposing functions of GDNF and Sprouty1 [J].

Basson, M. Albert ;

Watson-Johnson, Judy ;

Shakya, Reena ;

Akbulut, Simge ;

Hyink, Deborah ;

Costantini, Frank D. ;

Wilson, Patricia D. ;

Mason, Ivor J. ;

Licht, Jonathan D. .

DEVELOPMENTAL BIOLOGY, 2006, 299 (02) :466-477

[2] Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction [J].

Basson, MA ;

Akbulut, S ;

Watson-Johnson, J ;

Simon, R ;

Carroll, TJ ;

Shakya, R ;

Gross, I ;

Martin, GR ;

Lufkin, T ;

McMahon, AP ;

Wilson, PD ;

Costantini, FD ;

Mason, IJ ;

Licht, JD .

DEVELOPMENTAL CELL, 2005, 8 (02) :229-239

[3] ESSENTIAL ROLE FOR THE C-MET RECEPTOR IN THE MIGRATION OF MYOGENIC PRECURSOR CELLS INTO THE LIMB BUD [J].

BLADT, F ;

RIETHMACHER, D ;

ISENMANN, S ;

AGUZZI, A ;

BIRCHMEIER, C .

NATURE, 1995, 376 (6543) :768-771

[4] Tailbud-derived mesenchyme promotes urinary tract segmentation via BMP4 signaling [J].

Brenner-Anantharam, Andrea ;

Cebrian, Cristina ;

Guillaume, Richard ;

Hurtado, Romulo ;

Sun, Tung-Tien ;

Herzlinger, Doris .

DEVELOPMENT, 2007, 134 (10) :1967-1975

[5] Canonical WNT/β-catenin signaling is required for ureteric branching [J].

Bridgewater, Darren ;

Cox, Brian ;

Cain, Jason ;

Lau, Agnes ;

Athaide, Valerie ;

Gill, Paul S. ;

Kuure, Satu ;

Sainio, Kirsi ;

Rosenblum, Norman D. .

DEVELOPMENTAL BIOLOGY, 2008, 317 (01) :83-94

[6] TGF-β superfamily members modulate growth, branching, shaping, and patterning of the ureteric bud [J].

Bush, KT ;

Sakurai, H ;

Steer, DL ;

Leonard, MO ;

Sampogna, RV ;

Meyer, TN ;

Schwesinger, C ;

Qiao, JZ ;

Nigam, SK .

DEVELOPMENTAL BIOLOGY, 2004, 266 (02) :285-298

[7] Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system [J].

Carroll, TJ ;

Park, JS ;

Hayashi, S ;

Majumdar, A ;

McMahon, AP .

DEVELOPMENTAL CELL, 2005, 9 (02) :283-292

[8] Ret-Dependent Cell Rearrangements in the Wolffian Duct Epithelium Initiate Ureteric Bud Morphogenesis [J].

Chi, Xuan ;

Michos, Odysse ;

Shakya, Reena ;

Riccio, Paul ;

Enomoto, Hideki ;

Licht, Jonathan D. ;

Asai, Naoya ;

Takahashi, Masahide ;

Ohgami, Nobutaka ;

Kato, Masashi ;

Mendelsohn, Cathy ;

Costantini, Frank .

DEVELOPMENTAL CELL, 2009, 17 (02) :199-209

[9] A Transgenic Mouse That Reveals Cell Shape and Arrangement During Ureteric Bud Branching [J].

Chi, Xuan ;

Hadjantonakis, Anna-Katerina ;

Wu, Zaiqi ;

Hyink, Deborah ;

Costantini, Frank .

GENESIS, 2009, 47 (02) :61-66

[10] Wnt/β-catenin signaling in development and disease [J].

Clevers, Hans .

CELL, 2006, 127 (03) :469-480

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