Mystery solved: VSV-G-LVs do not allow efficient gene transfer into unstimulated T cells, B cells, and HSCs because they lack the LDL receptor

被引：150

作者：

Amirache, Fouzia ^{[1
]}

Levy, Camille ^{[1
]}

Costa, Caroline ^{[1
]}

Mangeot, Philippe-Emmanuel ^{[2
]}

Torbett, Bruce E. ^{[3
]}

Wang, Cathy X. ^{[3
]}

Negre, Didier ^{[1
]}

Cosset, Francois-Loic ^{[1
]}

Verhoeyen, Els ^{[1
,4
]}

机构：

[1] Univ Lyon 1, INSERM, U1111,Ctr Natl Rech Sci,Unite Mixte Rech 5308,Eco, Ctr Int Rech Infectiol,Enveloppe Virale & Ingn Re, F-69365 Lyon, France

[2] Scripps Res Inst, Ctr Int Rech Infectiol, Cellular Biol Viral Infect Team, La Jolla, CA 92037 USA

[3] Scripps Res Inst, Dept Mol & Expt Med, La Jolla, CA 92037 USA

[4] Ctr Mediterraneen Med Mol, INSERM, U1065, Equipe Controle Metab Morts Cellulaires, Nice, France

来源：

BLOOD | 2014年 / 123卷 / 09期

关键词：

LENTIVIRAL VECTOR; STABLE TRANSDUCTION; LYMPHOCYTES; VIRUS; THERAPY;

D O I：

10.1182/blood-2013-11-540641

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

引用

页码：1422 / 1424

页数：3

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