Lack of association between schizophrenia and the apolipoprotein E epsilon 4 allele

被引：23

作者：

Jonsson, E ^{[1
]}

Lannfelt, L ^{[1
]}

Engvall, B ^{[1
]}

Sedvall, G ^{[1
]}

机构：

[1] HUDDINGE HOSP, DEPT GERIATR MED, S-14186 HUDDINGE, SWEDEN

来源：

EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE | 1996年 / 246卷 / 04期

关键词：

schizophrenia; apolipoprotein E; association study; psychiatric genetics; Alzheimer's disease; ALZHEIMERS-DISEASE; TYPE-4; ALLELE; IMPAIRMENT; GENE;

D O I：

10.1007/BF02188951

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The association between the epsilon 4 allele of the apolipoprotein E (APOE) gene and Alzheimer's disease (AD) has been reported. In order to examine if the epsilon 4 allele may play a role also in schizophrenia, another mental disorder, patients (n = 87) and control subjects (n = 57) were genotyped for APOE. No significant difference was found between the groups. The data indicate that the APOE gene is not of major importance for the genesis of schizophrenia.

引用

页码：182 / 184

页数：3

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