TRIM9 is specifically expressed in the embryonic and adult nervous system

被引：46

作者：

Berti, C ^{[1
]}

Messali, S ^{[1
]}

Ballabio, A ^{[1
]}

Reymond, A ^{[1
]}

Meroni, G ^{[1
]}

机构：

[1] Telethon Inst Genet & Med, TIGEM, I-80131 Naples, Italy

来源：

MECHANISMS OF DEVELOPMENT | 2002年 / 113卷 / 02期

关键词：

tripartite motif; RING; B-box and coiled-coil domains; RING finger; B-box domain; embryonic nervous system; adult brain; cerebral cortex; dorsal thalamus; midbrain; pons; medulla oblongata; cerebellum; Purkinje cells; hippocampus;

D O I：

10.1016/S0925-4773(02)00013-8

中图分类号：

Q [生物科学];

学科分类号：

07 [理学]; 0710 [生物学]; 09 [农学];

摘要：

The TRIM family members are defined by the presence of the tripartite motif (RING, B-box and coiled-coil domains or RBCC). They have been implicated in a variety of processes,. such as regulation of development and oncogenesis. We report the expression analysis of a member of this family, TRIM9. Its expression is mainly confined to the central nervous system. The developing neocortex, the dorsal thalamus, the midbrain, the basal area of the hindbrain and spinal cord show high level of expression during embryogenesis, In adult brain, TRIM9 is detected in the Purkinje cells of the cerebellum. in the hippocampus. and in the cortex. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：159 / 162

页数：4

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