In Vivo Chlorhexidine Stabilization of Hybrid Layers of an Acetone-based Dentin Adhesive

被引:48
作者
Brackett, M. G. [1 ]
Tay, F. R. [2 ]
Brackett, W. W. [1 ]
Dib, A. [3 ]
Dipp, F. A. [3 ]
Mai, S. [4 ,5 ]
Pashley, D. H. [6 ]
机构
[1] Med Coll Georgia, Sch Dent, Dept Oral Rehabil, Augusta, GA 30912 USA
[2] Med Coll Georgia, Sch Dent, Dept Endodont, Augusta, GA 30912 USA
[3] Benemerita Univ Autonoma Puebla, Fac Estomatol, Puebla, Mexico
[4] Sun Yat Sen Univ, Dept Operat Dent & Endodont, Guanghua Sch Stomatol, Guangzhou 510275, Guangdong, Peoples R China
[5] Sun Yat Sen Univ, Inst Stomatol Res, Guangzhou 510275, Guangdong, Peoples R China
[6] Med Coll Georgia, Sch Dent, Dept Oral Biol & Maxillofacial Pathol, Augusta, GA 30912 USA
关键词
MATRIX METALLOPROTEINASES; NANOLEAKAGE; DEGRADATION; CARIES;
D O I
10.2341/08-103
中图分类号
R78 [口腔科学];
学科分类号
100302 [口腔临床医学];
摘要
The current in vivo study evaluated the degradation of dentin hybrid layers in deep occlusal-surface resin composite restorations using TEM. Caries-free premolars scheduled for extraction as part of orthodontic treatment were prepared and restored, then extracted after 12 months. The adhesive used was a single-bottle etch-and-rinse acetone-based product (Prime & Bond NT, Dentsply/Caulk). Control group restorations (n=8) were placed according to the manufacturer's instructions, while the experimental group received application of a 2% solution of chlorhexidine digluconate after etching and rinsing and prior to application of the adhesive. Extensive degradation was observed in all of the teeth in the control group after 12 months, while no degradation was observed in the experimental group. In vitro testing showed no significant difference in immediate microtensile bond strength between the control and experimental adhesive protocols.
引用
收藏
页码:379 / 383
页数:5
相关论文
共 14 条
[1]
The effect of chlorhexidine on dentin hybrid layers in vivo [J].
Brackett, W. W. ;
Tay, F. R. ;
Brackett, M. G. ;
Dib, A. ;
Sword, R. J. ;
Pashley, D. H. .
OPERATIVE DENTISTRY, 2007, 32 (02) :107-111
[2]
Microtensile dentin bond strength of self-etching resins: Effect of a hydrophobic layer [J].
Brackett, WW ;
Ito, S ;
Tay, FR ;
Haisch, LD ;
Pashley, DH .
OPERATIVE DENTISTRY, 2005, 30 (06) :733-738
[3]
In vivo preservation of the hybrid layer by chlorhexidine [J].
Carrilho, M. R. O. ;
Geraldeli, S. ;
Tay, F. ;
de Goes, M. F. ;
Carvalho, R. M. ;
Tjaderhane, L. ;
Reis, A. F. ;
Hebling, J. ;
Mazzoni, A. ;
Breschi, L. ;
Pashley, D. .
JOURNAL OF DENTAL RESEARCH, 2007, 86 (06) :529-533
[4]
The role of matrix metalloproteinases (MMPs) in human caries [J].
Chaussain-Miller, C ;
Fioretti, F ;
Goldberg, M ;
Menashi, S .
JOURNAL OF DENTAL RESEARCH, 2006, 85 (01) :22-32
[5]
Inhibition of the activities of matrix metalloproteinases 2, 8, and 9 by chlorhexidine [J].
Gendron, R ;
Grenier, D ;
Sorsa, T ;
Mayrand, D .
CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY, 1999, 6 (03) :437-439
[6]
The role of matrix metalloproteinases in the oral environment [J].
Hannas, Angelica R. ;
Pereira, Jose C. ;
Granjeiro, Jose M. ;
Tjaderhane, Leo .
ACTA ODONTOLOGICA SCANDINAVICA, 2007, 65 (01) :1-13
[7]
Hashimoto M, 2001, AM J DENT, V14, P211
[8]
Chlorhexidine arrests subclinical degradation of dentin hybrid layers in vivo [J].
Hebling, J ;
Pashley, DH ;
Tjäderhane, L ;
Tay, FR .
JOURNAL OF DENTAL RESEARCH, 2005, 84 (08) :741-746
[9]
THE PROMOTION OF ADHESION BY THE INFILTRATION OF MONOMERS INTO TOOTH SUBSTRATES [J].
NAKABAYASHI, N ;
KOJIMA, K ;
MASUHARA, E .
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1982, 16 (03) :265-273
[10]
Collagen degradation by host-derived enzymes during aging [J].
Pashley, DH ;
Tay, FR ;
Yiu, C ;
Hashimoto, M ;
Breschi, L ;
Carvalho, RM ;
Ito, S .
JOURNAL OF DENTAL RESEARCH, 2004, 83 (03) :216-221