The 3′ cis-acting genomic replication element of the severe acute respiratory syndrome coronavirus can function in the murine coronavirus genome

被引:45
作者
Goebel, SJ [1 ]
Taylor, J [1 ]
Masters, PS [1 ]
机构
[1] New York State Dept Hlth, Wadsworth Ctr Labs & Res, David Axelrod Inst, Albany, NY 12201 USA
关键词
D O I
10.1128/JVI.78.14.7846-7851.2004
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The 3' untranslated region (3' UTR) of the genome of the severe acute respiratory syndrome coronavirus can functionally replace its counterpart in the prototype group 2 coronavirus mouse hepatitis virus (MHV). By contrast, the 3' UTRs of representative group 1 or group 3 coronaviruses cannot operate as substitutes for the MHV 3' UTR.
引用
收藏
页码:7846 / 7851
页数:6
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