Microtubule capture: IQGAP and CLIP-170 expand the repertoire

被引：38

作者：

Gundersen, GG ^{[1
]}

机构：

[1] Columbia Univ, Dept Anat & Cell Biol, New York, NY 10032 USA

来源：

CURRENT BIOLOGY | 2002年 / 12卷 / 19期

关键词：

D O I：

10.1016/S0960-9822(02)01156-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Rho GTPases regulate microtubule capture near the cell cortex to polarize cells. What is surprising is the repertoire of interactions between proteins at the ends of microtubules and their cortical targets. The microtubule tip protein CLIP-170 has now been found to interact with the Cdc42/Rac effector IQGAP and mediate transient capture of microtubules.

引用

页码：R645 / R647

页数：3

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