Agenesis of the corpus callosum: etiology, clinical features, diagnostic methods and prognosis

Agenesis of the corpus callosum is a frequent congenital malformation with many etiologies and clinical features. It can occur as atl isolated defect which is usually sporadic, it is frequently, associated with other malformations, genetic syndromes and metabolic disorders. Ante- or postnatal diagnosis must be followed by a cafeful search for etiology, and it raises uncertain and difficult question with regard to pregnancy continuation and infant development. (C) 1999 Editions scientifiques et medicales Elsevier SAS.