Adaptations in skeletal muscle disuse or decreased-use atrophy

被引：83

作者：

Edgerton, VR

Roy, RR

Allen, DL

Monti, RJ

机构：

[1] Univ Calif Los Angeles, Dept Physiol Sci, Los Angeles, CA 90095 USA

[2] Univ Calif Los Angeles, Dept Neurobiol, Los Angeles, CA 90095 USA

[3] Univ Calif Los Angeles, Brain Res Inst, Los Angeles, CA 90095 USA

[4] Harvard Univ, Concord Field Stn, Dept Organism & Evolutionary Biol, Bedford, MA USA

[5] Univ Colorado, Dept Mol Cellular & Dev Biol, Boulder, CO 80309 USA

来源：

AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION | 2002年 / 81卷 / 11期

关键词：

physical activity; stress-strain; skeletal muscle plasticity; myogenesis; dystrophy;

D O I：

10.1097/00002060-200211001-00014

中图分类号：

R49 [康复医学];

学科分类号：

100215 [康复医学与理疗学];

摘要：

Those factors that seem to play some role in inducing adaptations of skeletal muscle in vivo are discussed. The role of myogenesis in maintaining and repairing muscle during atrophic and hypertrophic states is discussed, including pointing out that the modulation of myonuclear number is one means of adapting to varying chronic levels of neuromuscular activity. Finally, we point out the potential consequences of muscle atrophy on the control of movement and the susceptibility to fatigue.

引用

页码：S127 / S147

页数：21

共 185 条

[1]

INTERACTION OF CHRONIC CREATINE DEPLETION AND MUSCLE UNLOADING - EFFECTS ON POSTURAL AND LOCOMOTOR MUSCLES [J].