CMY-13, a novel inducible cephalosporinase encoded by an Escherichia coli plasmid

被引:44
作者
Miriagou, V
Tzouvelekis, LS
Villa, L
Lebessi, E
Vatopoulos, AC
Carattoli, A
Tzelepi, E
机构
[1] Hellenic Pasteur Inst, Bacteriol Lab, Athens 11527, Greece
[2] Univ Athens, Sch Med, Dept Microbiol, Athens, Greece
[3] Natl Sch Publ Hlth, Div Microbiol, Athens, Greece
[4] Ist Super Sanita, Dept Infect Dis, I-00161 Rome, Italy
关键词
D O I
10.1128/AAC.48.8.3172-3174.2004
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
An IncN plasmid (p541) from Escherichia coli carried a Citrobacter freundii-derived sequence of 4,252 bp which included an ampC-ampR region and was bound by two directly repeated IS26 elements. ampC encoded a novel cephalosporinase (CMY-13) with activity similar to that of CMY-2. AmpR was likely functional as indicated in induction experiments.
引用
收藏
页码:3172 / 3174
页数:3
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