Q fever epidemiology and pathogenesis

被引：92

作者：

Norlander, L ^{[1
]}

机构：

[1] Def Res Estab, Div NBC Def, SE-90182 Umea, Sweden

来源：

MICROBES AND INFECTION | 2000年 / 2卷 / 04期

关键词：

Q fever; Coxiella burnetii; epidemiology; pathogenesis; host response;

D O I：

10.1016/S1286-4579(00)00325-7

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The lungs are a port of entry and primary infectious focus of Coxiella burnetii, the obligate intracellular contagium of the worldwide zoonosis Q lever. The infectious process and immune response are characterised by studies in cell culture and animal systems. Following endocytosis, replication exclusively occurs in the phagolysosome. Several potential virulence factors are described. (C) 2000 Editions scientifiques et medicales Elsevier SAS.

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页码：417 / 424

页数：8

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