Transcriptional activation of adipogenesis

被引:111
作者
Wu, ZD [1 ]
Puigserver, P [1 ]
Spiegelman, BM [1 ]
机构
[1] Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Cell Biol, Boston, MA 02115 USA
关键词
D O I
10.1016/S0955-0674(99)00037-X
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Studies from the past several years have revealed that adipogenesis is controlled by an interplay of transcription factors, including members of the CCAAT/enhancer binding protein family and peroxisome proliferator activated receptor gamma. In addition to providing a new understanding of this aspect of the energy balance systems, these factors provide potential new targets for therapeutic intervention in metabolic diseases, such as obesity and type 2 diabetes mellitus.
引用
收藏
页码:689 / 694
页数:6
相关论文
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