Tandem aminocarbonylation/Pauson-Khand reaction of haloacetylenes

被引:28
作者
Balsells, J [1 ]
Moyano, A [1 ]
Riera, A [1 ]
Pericàs, MA [1 ]
机构
[1] Univ Barcelona, Dept Quim Organ, Unitat Recerca Sintesi Asimetr, E-08028 Barcelona, Spain
关键词
D O I
10.1021/ol991145h
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
[GRAPHICS] The dicobalt hexacarbonyl complex of 1-chloro-2-phenylacetylene decomposes in solution at room temperature affording similar amounts of two new complexes, to which the structures of a dichloro tetracobalt decacarbonyl complex of 1,4-diphenyl-1,3-butadiyne and of a 1-chloro-2-phenylacetylene acylcobalt complex have been tentatively assigned. The acyl complex can he efficiently trapped by amines, and the resulting aminocarbonylation products submitted to Pauson-Khand reaction to yield cyclopentenones with the regiocontrolled formation of five new bonds in a single synthetic operation.
引用
收藏
页码:1981 / 1984
页数:4
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