An efficient method for preparing the α-deuterated-α,β-unsaturated carbonyl compounds by reaction of stable phosphonium ylides with carbonyl compounds in deuterium oxide

被引：4

作者：

Hon, YS ^{[1
]}

Sheu, TR ^{[1
]}

Lee, CF ^{[1
]}

机构：

[1] Natl Chung Cheng Univ, Dept Chem, Chiayi 621, Taiwan

来源：

SYNTHETIC COMMUNICATIONS | 2000年 / 30卷 / 01期

关键词：

D O I：

10.1080/00397910008087298

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Carbonyl compounds reacted with stable phosphonium:ylides in D2O to give alpha-deuterated-alpha,beta-unsaturated carbonyl compounds in the same flask. The chemical yield and deuterium incorporation are excellent under our procedure. The fragile group like ozonide was compatible with our reaction condition.

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页码：97 / 118

页数：22

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