Fast folding experiments and the topography of protein folding energy landscapes

被引:94
作者
Wolynes, PG [1 ]
LutheySchulten, Z [1 ]
Onuchic, JN [1 ]
机构
[1] UNIV CALIF SAN DIEGO,DEPT PHYS,LA JOLLA,CA 92093
来源
CHEMISTRY & BIOLOGY | 1996年 / 3卷 / 06期
关键词
D O I
10.1016/S1074-5521(96)90090-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The rapid folding of certain proteins can be described theoretically using an energy landscape in the shape of a folding funnel. New techniques have allowed the examination of fast-folding events that occur in microseconds or less, and have tested the predictions of the theoretical models.
引用
收藏
页码:425 / 432
页数:8
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