Effect of plant matrix and fluid ethanol concentration on supercritical fluid extraction efficiency of schisandrin derivatives

被引:14
作者
Kim, Y
Choi, YH
Chin, YW
Jang, YP
Kim, YC
Kim, J [1 ]
Kim, JY
Joung, SN
Noh, MJ
Yoo, KP
机构
[1] Seoul Natl Univ, Coll Pharm, Seoul 151742, South Korea
[2] Seoul Natl Univ, Pharmaceut Sci Res Inst, Seoul 151742, South Korea
[3] Sogang Univ, Dept Chem Engn, Seoul 121742, South Korea
关键词
D O I
10.1093/chromsci/37.12.457
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
An investigation of the effect of plant matrix on the supercritical fluid extraction efficiency of five schisandrin derivatives is reported, exhibiting a great difference with respect to extraction efficiency depending on the matrix. Pure supercritical CO2 at 60°C and 34.0 MPa cannot fully recover schisandrin derivatives from the leaves as much as from the other matrices. Only 36.9% of these compounds are extracted from leaves of Schisandra chinensis by supercritical CO2 in comparison with organic solvent extraction. However, more than 80% of schisandrin derivatives are obtained from both stem and fruit parts. Ethanol addition also shows a different effect depending on plant matrix; that is, CO2 modified with 10% ethanol could enhance the yield of schisandrin derivatives from leaves by four times when compared with that of pure CO2, but it has little effect on both stems and fruits.
引用
收藏
页码:457 / 461
页数:5
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