Inhibitors of RT-PCR in serum

被引：15

作者：

Konet, DS ^{[1
]}

Mezencio, JMS ^{[1
]}

Babcock, G ^{[1
]}

Brown, F ^{[1
]}

机构：

[1] Plum Isl Anim Dis Ctr, Greenport, NY 11944 USA

来源：

JOURNAL OF VIROLOGICAL METHODS | 2000年 / 84卷 / 01期

关键词：

foot-and-mouth disease virus; RNA amplification; inhibitors;

D O I：

10.1016/S0166-0934(99)00131-7

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Amplification by RT-PCR of the RNA present in foot-and-mouth disease virus particles is inhibited by substances present in the sera of several species. This inhibition appears to be caused by a direct interaction of the substances with the RNA and not the enzymes used for its amplification. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：95 / 98

页数：4

共 4 条

[1] EFFECT OF VARIOUS INACTIVATING AGENTS ON VIRAL AND RIBONUCLEIC ACID INFECTIVITIES OF FOOT-AND-MOUTH DISEASE VIRUS AND ON ITS ATTACHMENT TO SUSCEPTIBLE CELLS [J].