Symmetrical dinuclear complexes with high DNA affinity based on [Ru(dpq)2(phen)]2+

被引：39

作者：

Aldrich-Wright, J ^{[1
]}

Brodie, C

Glazer, EC

Luedtke, NW

Elson-Schwab, L

Tor, Y

机构：

[1] Univ Western Sydney, Coll Sci Technol & Environm, Sch Sci Food & Hort, Penrith, NSW 1797, Australia

[2] Univ Calif San Diego, Dept Chem & Biochem, La Jolla, CA 92093 USA

来源：

CHEMICAL COMMUNICATIONS | 2004年 / 08期

关键词：

D O I：

10.1039/b316917k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Symmetrical homometallic dinuclear complexes of the type [{Ru(dpq)(2)}(2)(phen-SOS-phen)](4+), with a flexible 2-mercaptoethyl ether linker joining the two [Ru(dpq)(2)(phen)](2+)-based subunits, have DNA dissociation constants (K-d) in the nM range.

引用

页码：1018 / 1019

页数：2

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