When do lasses (longevity assurance genes) become CerS (ceramide synthases)? Insights into the regulation of ceramide synthesis

被引：357

作者：

Pewzner-Jung, Yael

Ben-Dor, Shifra

Futerman, Anthony H. ^{[1
]}

机构：

[1] Weizmann Inst Sci, Dept Biol Chem, IL-76100 Rehovot, Israel

[2] Weizmann Inst Sci, Dept Biol Serv, IL-76100 Rehovot, Israel

来源：

JOURNAL OF BIOLOGICAL CHEMISTRY | 2006年 / 281卷 / 35期

关键词：

D O I：

10.1074/jbc.R600010200

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：25001 / 25005

页数：5

共 57 条

[1] CERAMIDE SYNTHASE MEDIATES DAUNORUBICIN-INDUCED APOPTOSIS - AN ALTERNATIVE MECHANISM FOR GENERATING DEATH SIGNALS [J].

BOSE, R ;

VERHEIJ, M ;

HAIMOVITZFRIEDMAN, A ;

SCOTTO, K ;

FUKS, Z ;

KOLESNICK, R .

CELL, 1995, 82 (03) :405-414

[2]

BRANDWAGT BF, 2000, P NATL ACAD SCI USA, V597, P4691

[3] Ceramides and skin function [J].

Coderch, L ;

López, O ;

de la Maza, A ;

Parra, JL .

AMERICAN JOURNAL OF CLINICAL DERMATOLOGY, 2003, 4 (02) :107-129

[4]

COWARTLA, 2006, BIOCH J, V393, P733

[5]

DMELLO NP, 1994, J BIOL CHEM, V269, P15451

[6] Biochemical characterization of the reverse activity of rat brain ceramidase -: A CoA-independent and fumonisin B1-insensitive ceramide synthase [J].

El Bawab, S ;

Birbes, H ;

Roddy, P ;

Szulc, ZM ;

Bielawska, A ;

Hannun, YA .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (20) :16758-16766

[7]

Esch SW, 2003, CELL MOL BIOL, V49, P779

[8] Importance of C16 ceramide accumulation during apoptosis in prostate cancer cells [J].

Eto, M ;

Bennouna, J ;

Hunter, OC ;

Lotze, MT ;

Amoscato, AA .

INTERNATIONAL JOURNAL OF UROLOGY, 2006, 13 (02) :148-156

[9] C16 ceramide accumulates following androgen ablation in LNCaP prostate cancer cells [J].

Eto, M ;

Bennouna, J ;

Hunter, OC ;

Hershberger, PA ;

Kanto, T ;

Johnson, CS ;

Lotze, MT ;

Amoscato, AA .

PROSTATE, 2003, 57 (01) :66-79

[10] The complex life of simple sphingolipids [J].

Futerman, AH ;

Hannun, YA .

EMBO REPORTS, 2004, 5 (08) :777-782

← 1 2 3 4 5 6 →