tert-butoxycarbamate group:: a useful protecting group for the synthesis of orthogonally protected 'tropane-like' scaffolds

被引：8

作者：

Paparin, JL ^{[1
]}

Crévisy, C ^{[1
]}

Grée, R ^{[1
]}

机构：

[1] Ecole Natl Super Chim Rennes, CNRS, Lab Synth & Activat Biomol, F-35700 Rennes, France

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 14期

关键词：

4+3] cycloaddition; combinatorial chemistry; protecting groups; tropanes;

D O I：

10.1016/S0040-4039(00)00198-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first synthesis of N-Boc-protected tropanes by a [4+3] cycloaddition reaction is described. The Boc group has been cleanly removed demonstrating that this group would be very useful for the synthesis of 'tropane-like' scaffolds for combinatorial chemistry. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：2343 / 2346

页数：4

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