Primate models of AIDS

被引：48

作者：

Joag, SV

机构：

[1] JODI Res Inc, Wexford, PA USA

[2] Univ Kansas, Med Ctr, Sch Med, Marion Merrell Dow Lab Pathogenesis, Kansas City, KS 66103 USA

来源：

MICROBES AND INFECTION | 2000年 / 2卷 / 02期

关键词：

SIV; SHIV; macaque; HIV; lentivirus; simian;

D O I：

10.1016/S1286-4579(00)00266-5

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The primate models of AIDS provide insights into pathogenesis, transmission, and immune responses to infection and are useful in testing vaccines and drugs. The HIV-1/chimpanzee, SIVmac/macaque, and SHIV/macaque models are the most widely used. The advantages and drawbacks of these and other models are discussed. (C) 2000 Editions scientifiques et medicales Elsevier SAS.

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收藏

页码：223 / 229

页数：7

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