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Neuroleptic drugs in dementia: benefits and harm

被引：205
作者：
Ballard, Clive
Howard, Robert
机构：
[1] Kings Coll London, Med Res Council, Ctr Neurodegenerat Res, London SE5 8AF, England
[2] Kings Coll London, Wolfson Ctr Age Related Dis, London SE1 1UL, England
来源：
NATURE REVIEWS NEUROSCIENCE | 2006年 / 7卷 / 06期
关键词：
D O I：
10.1038/nrn1926
中图分类号：
Q189 [神经科学];
学科分类号：
071006 [神经生物学];
摘要：
Neuroleptic (antipsychotic) drugs are often used to treat psychiatric symptoms frequently seen in dementia, but their use is controversial. We present a new meta-analysis to assess the efficacy of these drugs for the treatment of psychiatric symptoms in Alzheimer's disease, and discuss the more limited evidence for their potential benefits in other dementias. We recommend that these treatments be limited to the short-term treatment of psychiatric symptoms associated with serious distress or risk.
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收藏
页码：492 / 500
页数：9
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