Pharmacological Effects of Glycyrrhiza spp. and Its Bioactive Constituents: Update and Review

被引：255

作者：

Hosseinzadeh, Hossein ^{[1
]}

Nassiri-Asl, Marjan ^{[2
]}

机构：

[1] Mashhad Univ Med Sci, Sch Pharm, Dept Pharmacodynam & Toxicol, Pharmaceut Res Ctr, Mashhad, Iran

[2] Univ Med Sci, Sch Med, Dept Pharmacol, Cellular & Mol Res Ctr, Qazvin, Iran

来源：

PHYTOTHERAPY RESEARCH | 2015年 / 29卷 / 12期

关键词：

licorice; Glycyrrhiza; antidiabetic; antiasthma; nephroprotective; FACTOR-KAPPA-B; REVERSIBLE ENCEPHALOPATHY SYNDROME; LIPOPROTEIN-LIPASE EXPRESSION; POSTOPERATIVE SORE THROAT; MAJOR ACTIVE ISOFLAVAN; LICORICE FLAVONOID OIL; GLABRA ROOT EXTRACT; 18-BETA-GLYCYRRHETINIC ACID; IN-VITRO; GLYCYRRHETINIC ACID;

D O I：

10.1002/ptr.5487

中图分类号：

R914 [药物化学];

学科分类号：

100705 [微生物与生化药学];

摘要：

The roots and rhizomes of various species of the perennial herb licorice (Glycyrrhiza) are used in traditional medicine for the treatment of several diseases. In experimental and clinical studies, licorice has been shown to have several pharmacological properties including antiinflammatory, antiviral, antimicrobial, antioxidative, antidiabetic, antiasthma, and anticancer activities as well as immunomodulatory, gastroprotective, hepatoprotective, neuroprotective, and cardioprotective effects. In recent years, several of the biochemical, molecular, and cellular mechanisms of licorice and its active components have also been demonstrated in experimental studies. In this review, we summarized the new phytochemical, pharmacological, and toxicological data from recent experimental and clinical studies of licorice and its bioactive constituents after our previous published review. Copyright (C) 2015 John Wiley & Sons, Ltd.

引用

页码：1868 / 1886

页数：19

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