EPR evidence of a triplet biradical in the photolysis of nifedipine

被引:10
作者
Buttafava, A [1 ]
Faucitano, A [1 ]
Fasani, E [1 ]
Albini, A [1 ]
Ricci, A [1 ]
机构
[1] Univ Pavia, Dipartimento Chim Organ, I-27100 Pavia, Italy
关键词
nifedipine; electron paramagnetic resonance; triplet; biradical;
D O I
10.1163/156856702320267136
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
UV irradiation of nifedipine leads to of triplet biradicals that can be detected by means of EPR spectroscopy.
引用
收藏
页码:231 / 237
页数:7
相关论文
共 10 条
[1]   STUDIES ON DIHYDROPYRIDINES .2. THE PHOTOCHEMICAL DISPROPORTIONATION OF 4-(2'-NITROPHENYL)-1,4-DIHYDROPYRIDINES [J].
BERSON, JA ;
BROWN, E .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1955, 77 (02) :447-450
[2]   EPR studies of the structure of transient radicals formed in photolytic reactions of some 2-nitrobenzyl compounds. Characterisation of aryl alkoxy aminoxyls and nitroaromatic radical-anions in the photolysis of caged ATP and related compounds [J].
Corrie, JET ;
Gilbert, BC ;
Munasinghe, VRN ;
Whitwood, AC .
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 2000, Royal Society of Chemistry (12) :2483-2491
[3]   USE OF THE ELECTRON-PARAMAGNETIC-RES HALF-FIELD TRANSITION TO DETERMINE THE INTERSPIN DISTANCE AND THE ORIENTATION OF THE INTERSPIN VECTOR IN SYSTEMS WITH 2 UNPAIRED ELECTRONS [J].
EATON, SS ;
MORE, KM ;
SAWANT, BM ;
EATON, GR .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1983, 105 (22) :6560-6567
[4]   Intramolecular and intermolecular photoinduced electron transfer in isomeric mesoporphyrin nitrobenzyl esters: Structure and solvent effects [J].
Fajari, L ;
Fors, P ;
Lang, K ;
Nonell, S ;
Trull, FR .
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 1996, 93 (2-3) :119-128
[5]  
FRITZ P, 1985, Z CHEM, V25, P222
[6]   Electron paramagnetic resonance study on the triplet species produced from 2-nitrobiphenyl derivatives by UV irradiation [J].
Higuchi, J ;
Fujisawa, M ;
Yokoyama, Y ;
Yagi, M .
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 1999, 124 (1-2) :53-65
[7]   SPECTROPHOTOMETRIC STUDY OF THE PHOTODECOMPOSITION KINETICS OF NIFEDIPINE [J].
MAJEED, IA ;
MURRAY, WJ ;
NEWTON, DW ;
OTHMAN, S ;
ALTURK, WA .
JOURNAL OF PHARMACY AND PHARMACOLOGY, 1987, 39 (12) :1044-1046
[8]   Conformational dynamics of 4-aryl-1,4-dihydropyridine calcium channel antagonists .1. Quantitation of C4-C1' bond rotational barriers [J].
Palmer, RB ;
Andersen, NH .
TETRAHEDRON, 1996, 52 (29) :9665-9680
[9]   REACTIVE RADICAL INTERMEDIATES FORMED FROM ILLUMINATED NIFEDIPINE [J].
STASKO, A ;
BREZOVA, V ;
BISKUPIC, S ;
ONDRIAS, K ;
MISIK, V .
FREE RADICAL BIOLOGY AND MEDICINE, 1994, 17 (06) :545-556
[10]   STEREOSELECTIVITY OF A POTENT CALCIUM-ANTAGONIST, 1-BENZYL-3-PYRROLIDINYL METHYL 2,6-DIMETHYL-4-(META-NITROPHENYL)-1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLATE [J].
TAMAZAWA, K ;
ARIMA, H ;
KOJIMA, T ;
ISOMURA, Y ;
OKADA, M ;
FUJITA, S ;
FURUYA, T ;
TAKENAKA, T ;
INAGAKI, O ;
TERAI, M .
JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (12) :2504-2511