Do B-cell chronic lymphocytic leukemia patients with Ig VH3-21 genes constitute a new subset of chronic lymphocytic leukemia?

被引：15

作者：

Nollet, F ^{[1
]}

Cauwelier, B ^{[1
]}

Billiet, J ^{[1
]}

Selleslag, D ^{[1
]}

Van Hoof, A ^{[1
]}

Louwagie, A ^{[1
]}

Criel, A ^{[1
]}

机构：

[1] Acad Hosp St Jan, Dept Hematol, B-8000 Brugge, Belgium

来源：

BLOOD | 2002年 / 100卷 / 03期

关键词：

D O I：

10.1182/blood-2002-03-0867

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1097 / 1098

页数：2

共 6 条

[1]

AUBIN J, 1995, LEUKEMIA, V9, P471

[2] Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors [J].

Fais, F ;

Ghiotto, F ;

Hashimoto, S ;

Sellars, B ;

Valetto, A ;

Allen, SL ;

Schulman, P ;

Vinciguerra, VP ;

Rai, K ;

Rassenti, LZ ;

Kipps, TJ ;

Dighiero, G ;

Schroeder, HW ;

Ferrarini, M ;

Chiorazzi, N .

JOURNAL OF CLINICAL INVESTIGATION, 1998, 102 (08) :1515-1525

[3] Unmutated Ig VH genes are associated with a more aggressive form of chronic lymphocytic leukemia [J].

Hamblin, TJ ;

Davis, Z ;

Gardiner, A ;

Oscier, DG ;

Stevenson, FK .

BLOOD, 1999, 94 (06) :1848-1854

[4]

Kröber A, 2001, BLOOD, V98, p358A

[5] STRUCTURE AND PHYSICAL MAP OF 64 VARIABLE SEGMENTS IN THE 3(I)0.8-MEGABASE REGION OF THE HUMAN-IMMUNOGLOBULIN HEAVY-CHAIN LOCUS [J].

MATSUDA, F ;

SHIN, EK ;

NAGAOKA, H ;

MATSUMURA, R ;

HAINO, M ;

FUKITA, Y ;

TAKAISHI, S ;

IMAI, T ;

RILEY, JH ;

ANAND, R ;

SOEDA, E ;

HONJO, T .

NATURE GENETICS, 1993, 3 (01) :88-94

[6] Somatically mutated Ig VH3-21 genes characterize a new subset of chronic lymphocytic leukemia [J].

Tobin, G ;

Thunberg, U ;

Johnson, A ;

Thörn, I ;

Söderberg, O ;

Hultdin, M ;

Botling, J ;

Enblad, G ;

Sällström, J ;

Sundström, C ;

Roos, G ;

Rosenquist, R .

BLOOD, 2002, 99 (06) :2262-2264

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