Ultraviolet light and cutaneous lupus

被引：46

作者：

Bijl, Marc ^{[1
]}

Kallenberg, Cees G. M. ^{[1
]}

机构：

[1] Univ Groningen, Med Ctr, Dept Internal Med, Div Clin Immunol, NL-9700 RB Groningen, Netherlands

来源：

LUPUS | 2006年 / 15卷 / 11期

关键词：

lupus; UVB; apoptosis; autoantibodies;

D O I：

10.1177/0961203306071705

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Exposure to ultraviolet (UV) light is one of the major factors known to trigger cutaneous disease activity in (systemic) lupus erythematosus patients. UV light, UVB in particular, is a potent inducer of apoptosis. Currently, disturbed clearance of apoptotic cells is one of the concepts explaining the development of inflammation in lupus patients. We review the role of apoptotic cells and autoantibodies in the pathogenesis of UVB induced skin lesions.

引用

页码：724 / 727

页数：4

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