Neural stem cells in the adult human brain

被引：295

作者：

Johansson, CB

Svensson, M

Wallstedt, L

Janson, AM

Frisén, J ^{[1
]}

机构：

[1] Karolinska Inst, Dept Cell & Mol Biol, SE-17177 Stockholm, Sweden

[2] Karolinska Inst, Dept Neurosci, SE-17177 Stockholm, Sweden

[3] Karolinska Inst, Neurosurg Sect, Dept Clin Neurosci, SE-17177 Stockholm, Sweden

[4] Karolinska Inst, Med Nobel Inst, SE-17177 Stockholm, Sweden

来源：

EXPERIMENTAL CELL RESEARCH | 1999年 / 253卷 / 02期

关键词：

D O I：

10.1006/excr.1999.4678

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

New neurons are continuously generated in certain regions of the adult brain. Studies in rodents have shown that new neurons are generated from self-renewing multipotent neural stem cells. Here we demonstrate that both the lateral ventricle wall and the hippocampus of the adult human brain harbor self-renewing cells capable of generating neurons, astrocytes, and oligodendrocytes in vitro, i.e., bona fide neural stem cells. (C) 1999 Academic Press.

引用

页码：733 / 736

页数：4

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