Effect of rescue or adjunctive percutaneous coronary intervention of the culprit artery after fibrinolytic administration on epicardial flow in nonculprit arteries

被引:21
作者
Gardner, GS
Frisch, DR
Murphy, SA
Kirtane, AJ
Giugliano, RP
Antman, EM
Braunwald, E
Gibson, CM
机构
[1] Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA USA
[2] Brigham & Womens Hosp, Dept Med, Boston, MA USA
关键词
D O I
10.1016/j.amjcard.2004.03.057
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We hypothesized that blood flow in noninfarct arteries would improve after percutaneous coronary intervention of the culprit artery in the setting of ST-elevation myocardial infarction (STEMI). The corrected Thrombolysis In Myocardial Infarction (TIMI) frame count was measured in 94 patients (102 arteries) enrolled in the INTEGRITI, ENTIRE, and FASTER trials of reduced dose fibrinolytic and glycoprotein IIb/IIIa inhibition. The corrected TIMI frame count in nonculprit arteries improved by 3.4 +/- 13.4 frames after percutaneous coronary intervention but remained significantly slower than flow in normal arteries. (C) 2004 by Excerpta Medica, Inc.
引用
收藏
页码:178 / 181
页数:4
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