Improvement in human semen quality after oral supplementation of vitamin C

被引:70
作者
Akmal, Mohammed
Qadri, J. Q.
Al-Waili, Noori S. [1 ]
Thangal, Shahiya
Haq, Afrozul
Saloom, Khelod Y.
机构
[1] Al Wailis Fdn Sci & Trading, Queens, NY USA
[2] Mafraq Hosp, Med Res & Specialized Testing Ctr, Abu Dhabi, U Arab Emirates
[3] Dubai Specialized Med Ctr & Res Labs, Dubai, U Arab Emirates
关键词
infertility; morphology; sperm count; sperm motility; vitamin C;
D O I
10.1089/jmf.2006.9.440
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
This study was carried out to monitor the effect of oral supplementation of vitamin C on various semen parameters in oligospermic, infer-tile, otherwise healthy individuals. Various semen parameters, including sperm motility, sperm count, and sperm morphology, were studied before and after the vitamin C treatment. A total of 13 infertile patients were included. Their ages ranged between 25 and 35 years. They had no genital infection or varicocel. Physical examination and other routine laboratory investigations were normal. General semen analysis revealed oligozoospermia (mean sperm count was 14.3 +/- 7.38 x 10(6) sperms/mL, mean sperm with normal morphology was 43 +/- 7.87%, and mean sperm motility was 31.2 +/- 9.61%). Testicular biopsy was not done. These patients received in an open trial of 1,000 mg of vitamin C twice daily for a maximum of 2 months. Results showed that the mean sperm count was increased to 32.8 +/- 10.3 x 10(6) sperms/mL (P <.001) after 2 months of vitamin C intake. The mean sperm motility was increased significantly to 60.1 +/- 8.47% (P <.001), and mean sperms with normal morphology increased significantly to 66.7 +/- 4.77% (P <.001). This study showed that vitamin C supplementation in infertile men might improve sperm count, sperm motility, and sperm morphology and might have a place as an additional supplement to improve the semen quality towards conception.
引用
收藏
页码:440 / 442
页数:3
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