Peptide-based stimuli-responsive biomaterials

被引：497

作者：

Mart, Robert J.

Osborne, Rachel D.

Stevens, Molly M.

Ulijn, Rein V.

机构：

[1] MIB, Manchester M1 7HS, Lancs, England

[2] Sch Mat, Manchester M1 7HS, Lancs, England

[3] Univ London Imperial Coll Sci Technol & Med, Dept Mat, London SW7 2AZ, England

[4] Univ London Imperial Coll Sci Technol & Med, Inst Biomed Engn, London SW7 2AZ, England

来源：

SOFT MATTER | 2006年 / 2卷 / 10期

关键词：

D O I：

10.1039/b607706d

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

This article explores recent advances in the design and engineering of materials wholly or principally constructed from peptides. We focus on materials that are able to respond to changes in their environment (pH, ionic strength, temperature, light, oxidation/reduction state, presence of small molecules or the catalytic activity of enzymes) by altering their macromolecular structure. Such peptide-based responsive biomaterials have exciting prospects for a variety of biomedical and bionanotechnology applications in drug delivery, bio-sensing and regenerative medicine.

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页码：822 / 835

页数：14

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