Structural brain variation and general intelligence

被引:374
作者
Haier, RJ
Jung, RE
Yeo, RA
Head, K
Alkire, MT
机构
[1] Univ Calif Irvine, Dept Pediat, Irvine, CA 92697 USA
[2] Univ New Mexico, Dept Neurol, Albuquerque, NM 87131 USA
[3] Univ New Mexico, MIND Inst, Albuquerque, NM 87131 USA
[4] Univ New Mexico, Dept Psychol, Albuquerque, NM 87131 USA
[5] Univ Calif Irvine, Med Ctr, Dept Anesthesiol, Orange, CA 92868 USA
关键词
IQ; brain volume; morphometry;
D O I
10.1016/j.neuroimage.2004.04.025
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Total brain volume accounts for about 16% of the variance in general intelligence scores (IQ), but how volumes of specific regions-of-interest (Rots) relate to IQ is not known. We used voxel-based morphometry (VBM) in two independent samples to identify substantial gray matter (GM) correlates of IQ. Based on statistical conjunction of both samples (N=47; P<0.05 corrected for multiple comparisons), more gray matter is associated with higher IQ in discrete Brodmann areas (BA) including frontal (BA 10, 46, 9), temporal (BA 21, 37, 22, 42), parietal (BA 43 and 3), and occipital (BA 19) lobes and near BA 39 for white matter (WM). These results underscore the distributed neural basis of intelligence and suggest a developmental course for volume-IQ relationships in adulthood. (C) 2004 Elsevier Inc. All rights reserved.
引用
收藏
页码:425 / 433
页数:9
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