Synthesis of the C1-C12-dihydropyran segment of the antitumor agent laulimalide by ring closing metathesis

被引：50

作者：

Mulzer, J ^{[1
]}

Hanbauer, M ^{[1
]}

机构：

[1] Univ Vienna, Inst Organ Chem, A-1090 Vienna, Austria

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 01期

关键词：

marine metabolites; antitumor compounds; metathesis; dihydropyran;

D O I：

10.1016/S0040-4039(99)02021-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A stereocontrolled synthesis of the C1-C12 fragment 3 of laulimalide utilizing a ring closing metathesis with Grubbs' catalyst as the key step is described. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：33 / 36

页数：4

共 32 条

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