A case of immunoglobulin G4-related chronic sclerosing sialadenitis and dacryoadenitis associated with tuberculosis

被引：44

作者：

Kawano, Mitsuhiro ^{[1
]}

Yamada, Kazunori ^{[1
]}

Kakuchi, Yasushi ^{[1
]}

Ito, Kiyoaki ^{[1
]}

Hamano, Ryoko ^{[1
]}

Fujii, Hiroshi ^{[1
]}

Inoue, Ryo ^{[1
]}

Matsumura, Masami ^{[1
]}

Takahira, Masayuki ^{[2
]}

Zen, Yoh ^{[3
]}

Yachie, Akihiro ^{[4
]}

Nakashima, Akikatsu ^{[5
]}

Yamagishi, Masakazu ^{[1
]}

机构：

[1] Kanazawa Univ, Grad Sch Med Sci, Dept Internal Med, Div Rheumatol, Kanazawa, Ishikawa 9208641, Japan

[2] Kanazawa Univ, Grad Sch Med Sci, Dept Ophthalmol, Kanazawa, Ishikawa 9208641, Japan

[3] Kanazawa Univ, Grad Sch Med Sci, Dept Human Pathol, Kanazawa, Ishikawa 9208641, Japan

[4] Kanazawa Univ, Grad Sch Med Sci, Dept Pediat, Kanazawa, Ishikawa 9208641, Japan

[5] Kanazawa Univ, Saiseikai Kanazawa Hosp, Dept Internal Med, Kanazawa, Ishikawa 9208641, Japan

来源：

MODERN RHEUMATOLOGY | 2009年 / 19卷 / 01期

关键词：

Immunoglobulin G4 (IgG4); Mikulicz's syndrome; Sclerosing dacryoadenitis; Sclerosing sialadenitis; Tuberculosis;

D O I：

10.1007/s10165-008-0127-z

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

We describe a 64-year-old woman with chronic sclerosing sialadenitis and dacryoadenitis, which developed during treatment for cervical lymph node tuberculosis. Anti-tuberculosis treatment did not improve the swelling in the lacrimal and submandibular glands, and a biopsy specimen of the lacrimal gland showed inflammation, with abundant lymphoid follicles with fibrosis and granuloma without caseous necrosis. Immunohistological examination of a repeat biopsy specimen showed abundant immunoglobulin (Ig) G4-positive plasma cell infiltration. Corticosteroid therapy improved the salivary gland swelling without reactivation of the tuberculosis. This case suggests that an abnormal immunological reaction to tuberculosis may be one of the etiological candidates for IgG4-related disease.

引用

页码：87 / 90

页数：4

共 16 条

[1]

Decline in total serum IgE after treatment for tuberculosis [J].