Synthesis of the kappa-agonist CJ-15,161 via a palladium-catalyzed cross-coupling reaction

被引：14

作者：

Ghosh, A ^{[1
]}

Sieser, JE ^{[1
]}

Caron, S ^{[1
]}

Watson, TJN ^{[1
]}

机构：

[1] Pfizer Global Res & Dev, Chem Res & Dev, Groton, CT 06340 USA

来源：

CHEMICAL COMMUNICATIONS | 2002年 / 15期

关键词：

D O I：

10.1039/b204844b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Syntheses of CJ-15,161 (1) involving intermolecular N-arylation of an appropriately functionalized diamine, obtained from the precursor alpha-amino acids or, more conveniently, from the corresponding 1,2-amino alcohols via 1,2,3-oxathiazolidine-2,2-dioxide 22, are reported.

引用

页码：1644 / 1645

页数：2

共 24 条

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