Hollow metallic micromachined needles with multiple output ports

被引:12
作者
Brazzle, JD [1 ]
Mohanty, S [1 ]
Frazier, AB [1 ]
机构
[1] Univ Utah, Dept Bioengn, Salt Lake City, UT 84112 USA
来源
MICROFLUIDIC DEVICES AND SYSTEMS II | 1999年 / 3877卷
关键词
microneedles; Navier-Stokes; microchannels; fluid modeling; micromachining; drug delivery;
D O I
10.1117/12.359344
中图分类号
TH [机械、仪表工业];
学科分类号
0802 ;
摘要
In this paper, hollow metallic micromachined needles with multiple output ports are designed, fabricated, characterized, and packaged. The hollow metallic needles include design features such as tapered needle tips and multiple output ports on the bottom and top of each needle. The needle tip and shaft are formed by microelectroformed metal. The now characteristics of the needles are currently being experimentally investigated and modeled using a finite element numerical model. The experimental results and theoretical models will be presented as part of this paper. The micromachined needles can be fabricated on a variety of substrates and can use micro-electroformed palladium as the structural material. The use of palladium as a structural material provides high mechanical strength and durability, as well as, biocompatibility for use in biomedical applications. The cross-sectional dimensions of individual needle tips begin at less than 10 mu m in width and 15 mu m in height and then taper to 200 mu m in width and 60 mu m in height. The significance of this work includes the development of hollow metallic micromachined needles for biomedical applications, as well as, a discussion of structural, fluidic, and packaging design considerations.
引用
收藏
页码:257 / 266
页数:10
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