C/EBPα mutations in lung cancer

被引:14
作者
Costa, Daniel B.
Dayaram, Tajhal
D'Alo, Francesco
Wouters, Bas J.
Tenen, Daniel G.
Meyerson, Matthew
Tsao, Ming-Sound
Halmos, Balazs
机构
[1] Harvard Med Sch, Beth Israel Deaconess Med Ctr, Div Hematol Oncol, Boston, MA 02215 USA
[2] Harvard Med Sch, Dana Farber Canc Inst, Boston, MA 02115 USA
[3] Princess Margaret Hosp, Toronto, ON M4X 1K9, Canada
[4] Univ Toronto, Toronto, ON, Canada
[5] Case Western Reserve Univ, Div Hematol Oncol, Cleveland, OH 44106 USA
关键词
lung cancer; C/EBP alpha; mutation; methylation; epigenetic; transcription factor;
D O I
10.1016/j.lungcan.2006.04.011
中图分类号
R73 [肿瘤学];
学科分类号
100214 [肿瘤学];
摘要
引用
收藏
页码:253 / 254
页数:2
相关论文
共 8 条
[1]
Respiratory failure due to differentiation arrest and expansion of alveolar cells following lung-specific loss of the transcription factor C/EBPα in mice [J].
Bassères, DS ;
Levantini, E ;
Ji, HB ;
Monti, S ;
Elf, S ;
Dayaram, T ;
Fenyus, M ;
Kocher, O ;
Golub, T ;
Wong, KK ;
Halmos, B ;
Tenen, DG .
MOLECULAR AND CELLULAR BIOLOGY, 2006, 26 (03) :1109-1123
[2]
CEBPA mutations in younger adults with acute myeloid leukemia and normal cytogenetics:: Prognostic relevance and analysis of cooperating mutations [J].
Fröhling, S ;
Schlenk, RE ;
Stolze, I ;
Bihlmayr, J ;
Benner, A ;
Kreitmeier, S ;
Tobis, K ;
Döhner, H ;
Döhner, K .
JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (04) :624-633
[3]
Mutations in the gene encoding the transcription factor CCAAT/enhancer binding protein α in myelodysplastic syndromes and acute myeloid leukemias [J].
Gombart, AF ;
Hofmann, WK ;
Kawano, S ;
Takeuchi, S ;
Krug, U ;
Kwok, SH ;
Larsen, RJ ;
Asou, H ;
Miller, CW ;
Hoelzer, D ;
Koeffler, HP .
BLOOD, 2002, 99 (04) :1332-1340
[4]
Halmos B, 2002, CANCER RES, V62, P528
[5]
Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-α (C/EBPα), in acute myeloid leukemia [J].
Pabst, T ;
Mueller, BU ;
Zhang, P ;
Radomska, HS ;
Narravula, S ;
Schnittger, S ;
Behre, G ;
Hiddemann, W ;
Tenen, DG .
NATURE GENETICS, 2001, 27 (03) :263-270
[6]
AML1-ETO downregulates the granulocytic differentiation factor C/EBPα in t(8;21) myeloid leukemia [J].
Pabst, T ;
Mueller, BU ;
Harakawa, N ;
Schoch, C ;
Haferlach, T ;
Behre, G ;
Hiddemann, W ;
Zhang, DE ;
Tenen, DG .
NATURE MEDICINE, 2001, 7 (04) :444-451
[7]
Favorable prognostic significance of CEBPA mutations in patients with de novo acute myeloid leukemia:: a study from the Acute Leukemia French Association (ALFA) [J].
Preudhomme, C ;
Sagot, C ;
Boissel, N ;
Cayuela, JM ;
Tigaud, I ;
de Botton, S ;
Thomas, X ;
Raffoux, E ;
Lamandin, C ;
Castaigne, S ;
Fenaux, P ;
Dombret, H .
BLOOD, 2002, 100 (08) :2717-2723
[8]
Epigenetic modulation of tumor suppressor CCAAT/Enhancer binding protein a activity in lung cancer [J].
Tada, T ;
Brena, RMT ;
Hackanson, B ;
Morrison, C ;
Otterson, GA ;
Plass, C .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2006, 98 (06) :396-406