Pathophysiology of Neuromuscular Respiratory Diseases

被引：20

作者：

Benditt, Joshua O. ^{[1
]}

机构：

[1] Univ Washington, Sch Med, Dept Med, 1959 NE Pacific St, Seattle, WA 98119 USA

来源：

CLINICS IN CHEST MEDICINE | 2018年 / 39卷 / 02期

关键词：

Neuromuscular disease; Pathophysiology of neuromuscular disease; Respiratory failure; Pulmonary function assessment; Amyotrophic lateral sclerosis; Muscular dystrophies; Spinal cord injury; DUCHENNE MUSCULAR-DYSTROPHY; PULMONARY COMPLICATIONS; CONSENSUS STATEMENT; MUSCLE STRENGTH; SLEEP; DYSFUNCTION; VENTILATION; MANAGEMENT; HYPOVENTILATION; TRACHEOSTOMY;

D O I：

10.1016/j.ccm.2018.01.011

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

100201 [内科学];

摘要：

Gas exchange between the atmosphere and the human body depends on the lungs and the function of the respiratory pump. The respiratory pump consists of the respiratory control center located in the brain, bony rib cage, diaphragm, and intercostal, accessory, and abdominal muscles. A variety of receptors and feedback pathways serve to fine-tune ventilation to metabolic demands. Appropriate evaluation and interventions can prevent respiratory complications and prolong life in individuals with neuromuscular diseases. This article discusses the normal function of the respiratory pump, general pathophysiologic issues, and abnormalities in more common neuromuscular diseases.

引用

页码：297 / +

页数：13

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