Bile ducts as a source of pancreatic β cells

被引:13
作者
Burke, ZD [1 ]
Shen, CN [1 ]
Tosh, D [1 ]
机构
[1] Univ Bath, Ctr Regenerat Med, Dept Biol & Biochem, Bath BA2 7AY, Avon, England
关键词
D O I
10.1002/bies.20090
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In recent years, there have been a number of well-documented examples demonstrating that one cell type can be converted to another. Two such examples are the appearance of ectopic pancreas in the liver and formation of hepatic tissue in the pancreas. The conversion of liver to pancreas raises the intriguing possibility of generating insulin-producing beta cells for therapeutic transplantation into diabetics. There is now a striking addition to the growing list of pancreatic conversions: the formation of pancreatic tissue in the developing biliary system.((1)) (C) 2004 Wiley Periodicals, Inc.
引用
收藏
页码:932 / 937
页数:6
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