A Graphene Platform for Sensing Biomolecules

被引：2051

作者：

Lu, Chun-Hua ^{[1
]}

Yang, Huang-Hao ^{[1
,2
]}

Zhu, Chun-Ling ^{[2
]}

Chen, Xi ^{[1
]}

Chen, Guo-Nan ^{[1
]}

机构：

[1] Fuzhou Univ, Coll Chem & Chem Engn, Key Lab Anal & Detect Technol Food Safety MOE, Fuzhou 350002, Peoples R China

[2] SOA, Inst Oceanog 1, Qingdao 266061, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 26期

基金：

中国国家自然科学基金;

关键词：

aptamers; biosensors; DNA; graphene; proteins; WALLED CARBON NANOTUBES; DNA; NANODIAMONDS; FILMS; OXIDE;

D O I：

10.1002/anie.200901479

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Sensitive platform: The use of graphene oxide (GO) as a platform for the sensitive and selective detection of DNA and proteins is presented. The interaction of GO and dyelabeled single-stranded DNA leads to quenching of the dye fluorescence. Conversely, the presence of a target DNA or protein leads to the binding of the dye-labeled DNA and target, releasing the DNA from GO, thereby restoring the dye fluorescence (see picture). © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：4785 / 4787

页数：3

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