Role of endocervical curettage in the preoperative staging of endometrial carcinoma

被引：6

作者：

Bijen, Claudia B. M. ^{[1
]}

de Bock, Geertruida H. ^{[2
]}

ten Hoor, Klaske A. ^{[3
]}

Nijman, Hans W. ^{[1
]}

Hollema, Harry ^{[3
]}

Mourits, Marian J. E. ^{[1
]}

机构：

[1] Univ Groningen, Univ Med Ctr Groningen, Dept Gynecol Oncol, NL-9700 RB Groningen, Netherlands

[2] Univ Groningen, Univ Med Ctr Groningen, Dept Epidemiol, NL-9700 RB Groningen, Netherlands

[3] Univ Groningen, Univ Med Ctr Groningen, Dept Pathol, NL-9700 RB Groningen, Netherlands

来源：

GYNECOLOGIC ONCOLOGY | 2009年 / 112卷 / 03期

关键词：

Endometrial neoplasm; Neoplasm staging; Curettage; GYNECOLOGIC-ONCOLOGY-GROUP; CERVICAL INVOLVEMENT; RANDOMIZED-TRIAL; CANCER; ADENOCARCINOMA; MANAGEMENT; DIAGNOSIS; ACCURACY; CYTOLOGY; SURGERY;

D O I：

10.1016/j.ygyno.2008.11.023

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

Objective, The presence of cervical involvement is important to establish a rational treatment for endometrial cancer patients. We investigated the value of preoperative endocervical curettage (ECC) in predicting cervical involvement. Methods. Preoperative ECC of 290 patients with clinical stage I epithelial endometrial cancer was compared with histopathology of the uterus. Results, Amongst all ECCs, 245 (84.5%) were negative and 45 (15.5%) were positive for endometrial cancer. in the uterine specimen, cervical involvement was found in 20% (58/290). PPV and NPV of ECC were 86.7% and 92.2%. False negative and false positive ECC occurred in 6.6% and 2.1%, Of all patients with positive ECC, 46.7% had FIGO stage II disease and 46.7% had extra uterine tumor spread (FIGO III, IV). Conclusion. ECC is an acceptable diagnostic tool to predict the presence or absence of cervical involvement in early stage endometrial cancer patients. (C) 2008 Elsevier Inc. All rights reserved.

引用

页码：521 / 525

页数：5

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