Caution on pedigree haplotype inference with software that assumes linkage equilibrium

被引:84
作者
Schaid, DJ
McDonnell, SK
Wang, L
Cunningham, JM
Thibodeau, SN
机构
[1] Mayo Clin & Mayo Fdn, Biostat Sect, Dept Hlth Sci Res, Rochester, MN 55905 USA
[2] Mayo Clin & Mayo Fdn, Dept Lab Med & Pathol, Rochester, MN 55905 USA
关键词
D O I
10.1086/342666
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
引用
收藏
页码:992 / 995
页数:4
相关论文
共 13 条
[1]   GOLD - Graphical Overview of Linkage Disequilibrium [J].
Abecasis, GR ;
Cookson, WOC .
BIOINFORMATICS, 2000, 16 (02) :182-183
[2]   Germline mutations in the ribonuclease L gene in families showing linkage with HPC1 [J].
Carpten, J ;
Nupponen, N ;
Isaacs, S ;
Sood, R ;
Robbins, C ;
Xu, J ;
Faruque, M ;
Moses, T ;
Ewing, C ;
Gillanders, E ;
Hu, P ;
Buinovszky, P ;
Makalowska, I ;
Baffoe-Bonnie, A ;
Faith, D ;
Smith, J ;
Stephan, D ;
Wiley, K ;
Brownstein, M ;
Gildea, D ;
Kelly, B ;
Jenkins, R ;
Hostetter, G ;
Matikainen, M ;
Schleutker, J ;
Klinger, K ;
Connors, T ;
Xiang, Y ;
Wang, Z ;
De Marzo, A ;
Papadopoulos, N ;
Kallioniemi, OP ;
Burk, R ;
Meyers, D ;
Grönberg, H ;
Meltzer, P ;
Silverman, R ;
Bailey-Wilson, J ;
Walsh, P ;
Isaacs, W ;
Trent, J .
NATURE GENETICS, 2002, 30 (02) :181-184
[3]  
EXCOFFIER L, 1995, MOL BIOL EVOL, V12, P921
[4]   Accuracy of haplotype frequency estimation for biallelic loci, via the expectation-maximization algorithm for unphased diploid genotype data [J].
Fallin, D ;
Schork, NJ .
AMERICAN JOURNAL OF HUMAN GENETICS, 2000, 67 (04) :947-959
[5]   HAPLO - A PROGRAM USING THE EM ALGORITHM TO ESTIMATE THE FREQUENCIES OF MULTISITE HAPLOTYPES [J].
HAWLEY, ME ;
KIDD, KK .
JOURNAL OF HEREDITY, 1995, 86 (05) :409-411
[6]  
Kruglyak L, 1996, AM J HUM GENET, V58, P1347
[7]  
LONG JC, 1995, AM J HUM GENET, V56, P799
[8]   Linkage disequilibrium in the human genome [J].
Reich, DE ;
Cargill, M ;
Bolk, S ;
Ireland, J ;
Sabeti, PC ;
Richter, DJ ;
Lavery, T ;
Kouyoumjian, R ;
Farhadian, SF ;
Ward, R ;
Lander, ES .
NATURE, 2001, 411 (6834) :199-204
[9]   Haplotyping and estimation of haplotype frequencies for closely linked biallelic multilocus genetic phenotypes including nuclear family information [J].
Rohde, K ;
Fuerst, R .
HUMAN MUTATION, 2001, 17 (04) :289-295
[10]   Score tests for association between traits and haplotypes when linkage phase is ambiguous [J].
Schaid, DJ ;
Rowland, CM ;
Tines, DE ;
Jacobson, RM ;
Poland, GA .
AMERICAN JOURNAL OF HUMAN GENETICS, 2002, 70 (02) :425-434