Multiple antibiotic resistance in Stenotrophomonas maltophilia

被引:135
作者
Alonso, A [1 ]
Martinez, JL [1 ]
机构
[1] CSIC,BANCO CELULAS,CTR NACL BIOTECNOL,E-28049 MADRID,SPAIN
关键词
D O I
10.1128/AAC.41.5.1140
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
A cryptic multidrug resistance (MDR) system in Stenotrophomonas maltophilia, the expression of which is selectable by tetracycline is described. Tetracycline resistance aas the consequence of active efflux of the antibiotic, and it was associated with resistance to quinolones and chloramphenicol, but not to aminoglycosides or beta-lactam antibiotics, MDR is linked to the expression of an outer membrane protein (OMP54) both in a model system and in multidrug-resistant clinical isolates.
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页码:1140 / 1142
页数:3
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