Directed evolution of hybrid enzymes: Evolving enantioselectivity of an achiral Rh-complex anchored to a protein

被引：129

作者：

Reetz, Manfred T. ^{[1
]}

Peyralans, Jerome J. -P. ^{[1
]}

Maichele, Andrea ^{[1
]}

Fu, Yu ^{[1
]}

Maywald, Matthias ^{[1
]}

机构：

[1] Max Planck Inst Kohlenforsch, D-45470 Mulheim, Germany

来源：

CHEMICAL COMMUNICATIONS | 2006年 / 41期

关键词：

D O I：

10.1039/b610461d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The concept of utilizing the methods of directed evolution for tuning the enantioselectivity of synthetic achiral metal - ligand centers anchored to proteins has been implemented experimentally for the first time.

引用

页码：4318 / 4320

页数：3

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