Consequence of therapy discontinuation in bisphosphonate-associated osteonecrosis of the jaws

被引:14
作者
Gallego, Lorena [1 ]
Junquera, Luis [1 ]
机构
[1] Univ Cent Hosp, Dept Oral & Maxillofacial Surg, Oviedo 33009, Spain
关键词
Bisphosphonate discontinuation; Multiple myelomas; Pathological fractures;
D O I
10.1016/j.bjoms.2008.05.011
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
We report a patient with bisphosphonate-associated osteonecrosis of the jaws who developed pathological fractures of the upper and lower extremities after the suspension of treatment with bisphosphonates. Temporary discontinuation of the drugs does not alter the clinical course of the disease. and Could result in the recurrence of bone pain and the progression of metastases or osteolytic lesions. (C) 2008 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:67 / 68
页数:2
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