The Eighth Edition AJCC Cancer Staging Manual: Continuing to build a bridge from a population-based to a more "personalized" approach to cancer staging

被引：5191

作者：

Amin, Mahul B. ^{[1
]}

Greene, Frederick L. ^{[2
]}

Edge, Stephen B. ^{[3
,4
]}

Compton, Carolyn C. ^{[5
,6
]}

Gershenwald, Jeffrey E. ^{[7
]}

Brookland, Robert K. ^{[8
]}

Meyer, Laura ^{[9
]}

Gress, Donna M. ^{[9
]}

Byrd, David R. ^{[10
,11
]}

Winchester, David P. ^{[9
]}

机构：

[1] Univ Tennessee, Ctr Hlth Sci, UTHSC Gerwin Chair Canc Res, Dept Pathol & Lab Med, Memphis, TN 38163 USA

[2] Levine Canc Inst, Canc Data Serv, Charlotte, NC USA

[3] Roswell Pk Canc Inst, Healthcare Outcomes & Policy, Dept Canc Prevent & Control, Buffalo, NY 14263 USA

[4] Roswell Pk Canc Inst, Dept Surg Oncol, Oncol, Buffalo, NY 14263 USA

[5] Arizona State Univ, Complex Adapt Syst Initiat, Scottsdale, AZ USA

[6] Mayo Clin, Lab Med & Pathol, Rochester, MN USA

[7] Univ Texas MD Anderson Canc Ctr, Surg & Canc Biol, Houston, TX 77030 USA

[8] Greater Baltimore Med Ctr, Baltimore, MD USA

[9] Amer Joint Comm Canc, Chicago, IL USA

[10] Univ Washington, Surg Oncol, Seattle, WA 98195 USA

[11] Univ Washington, Surg, Seattle, WA 98195 USA

来源：

CA-A CANCER JOURNAL FOR CLINICIANS | 2017年 / 67卷 / 02期

关键词：

American Joint Committee on Cancer (AJCC); application programing interface; cancer stage; component content management system; electronic health record; precision medicine; prognostic factors; risk assessment models; TNM staging;

D O I：

10.3322/caac.21388

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The American Joint Committee on Cancer (AJCC) staging manual has become the benchmark for classifying patients with cancer, defining prognosis, and determining the best treatment approaches. Many view the primary role of the tumor, lymph node, metastasis (TNM) system as that of a standardized classification system for evaluating cancer at a population level in terms of the extent of disease, both at initial presentation and after surgical treatment, and the overall impact of improvements in cancer treatment. The rapid evolution of knowledge in cancer biology and the discovery and validation of biologic factors that predict cancer outcome and response to treatment with better accuracy have led some cancer experts to question the utility of a TNM-based approach in clinical care at an individualized patient level. In the Eighth Edition of the AJCC Cancer Staging Manual, the goal of including relevant, nonanatomic (including molecular) factors has been foremost, although changes are made only when there is strong evidence for inclusion. The editorial board viewed this iteration as a proactive effort to continue to build the important bridge from a population-based to a more personalized approach to patient classification, one that forms the conceptual framework and foundation of cancer staging in the era of precision molecular oncology. The AJCC promulgates best staging practices through each new edition in an effort to provide cancer care providers with a powerful, knowledge-based resource for the battle against cancer. In this commentary, the authors highlight the overall organizational and structural changes as well as what's new in the Eighth Edition. It is hoped that this information will provide the reader with a better understanding of the rationale behind the aggregate proposed changes and the exciting developments in the upcoming edition. (C) 2017 American Cancer Society.

引用

页码：93 / 99

页数：7

共 11 条

[1]

Amin M.B., 2017, AM JOINT COMMITTEE C, V8th

[2]

[Anonymous], 1977, MANUAL STAGING CANC

[3]

Beahrs O.H., 1992, MANUAL STAGING CANC, V4th

[4]

Beahrs OH, 1983, MANUAL STAGING CANC

[5]

Beahrs OH., 1988, Manual for Staging of Cancer, V3rd

[6]

Bierley JD., 2017, TNM classification of malignant tumours, V8th, DOI DOI 10.1002/EJOC.201200111

[7]

Denoix PF, 1952, B I NAT HYG PARIS, V7, P743

[8]

Edge S.B., 2010, AJCC cancer staging manual, V649

[9]

Fleming ID, 1997, AJCC CANC STAGING MA

[10]

Greene F., 2002, AJCC cancer staging handbook: From the AJCC cancer staging manual, V6th

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