Preparation of chitosan derivative with polyethylene glycol side chains for porous structure without specific processing technique

被引：30

作者：

Huang, Meifang

Liu, Li

Zhang, Guobin

Yuan, Guangbi

Fang, Yue'e

机构：

[1] Univ Sci & Technol China, Dept Polymer Sci & Engn, Hefei 230026, Anhui, Peoples R China

[2] Univ Sci & Technol China, Natl Synchrotron Radiat Lab, Hefei 230026, Anhui, Peoples R China

来源：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2006年 / 38卷 / 3-5期

基金：

中国国家自然科学基金;

关键词：

chitosan; polyethylene glycol; graft copolymers; porous structure;

D O I：

10.1016/j.ijbiomac.2006.02.008

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

The graft copolymer, chitosan-g-polyethylene glycol (PEG), was prepared through graft polymerization of PEG chains to chitosan due to the esterification reaction between PEG and 6-O-succinate-N-phthaloyl-chitosan (PHCSSA). The graft copolymer with porous structure was observed from scanning, electron micrographs. It is a potential method to combine chitosan with the hydrophilic synthetic polymers. The graft reaction was carried out in homogeneous system and yielded copolymers with high grafting content. FTIR, NMR, XRD, DSC, spectrofluorophotometer and SEM were detected to characterize the copolymer. (c) 2006 Elsevier B.V. All rights reserved.

引用

收藏

页码：191 / 196

页数：6

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