Evaluation of the roles of reactive species, heat, and UV radiation in the inactivation of bacterial cells by air plasmas at atmospheric pressure

被引:664
作者
Laroussi, M [1 ]
Leipold, F [1 ]
机构
[1] Old Dominion Univ, Dept Elect & Comp Engn, Norfolk, VA 23529 USA
关键词
microorganism; air plasma; discharge; reactive species; sterilization;
D O I
10.1016/j.ijms.2003.11.016
中图分类号
O64 [物理化学(理论化学)、化学物理学]; O56 [分子物理学、原子物理学];
学科分类号
070203 ; 070304 ; 081704 ; 1406 ;
摘要
Recently. non-equilibrium. atmospheric pressure air plasmas have been shown to possess excellent germicidal properties. A number of studies have shown that air plasmas are capable of inactivating a wide range of microorganisms in the matter of few seconds to few minutes. However. until now little information regarding quantitative measurements of the various plasma agents that can potentially participate in the inactivation process has been published. In this paper, emission spectroscopy and gas detection are used to evaluate important plasma inactivation factors such as UV radiation and reactive species. Our measurements show that for non-equilibrium, atmospheric pressure air plasmas. it is the oxygen-based and nitrogen-based reactive species that play the most important role in the inactivation process. (C) 2004 Elsevier B.V. All rights reserved.
引用
收藏
页码:81 / 86
页数:6
相关论文
共 14 条
[1]  
Bettleheim F. A., 1995, INTRO GEN ORGANIC BI
[2]   Bacterial decontamination using ambient pressure nonthermal discharges [J].
Birmingham, JG ;
Hammerstrom, DJ .
IEEE TRANSACTIONS ON PLASMA SCIENCE, 2000, 28 (01) :51-55
[3]  
BLOCK SS, 1992, ENCY MICROBIOLOGY, V4, P87
[4]   Decontamination of chemical and biological warfare, (CBW) agents using an atmospheric pressure plasma jet (APPJ) [J].
Herrmann, HW ;
Henins, I ;
Park, J ;
Selwyn, GS .
PHYSICS OF PLASMAS, 1999, 6 (05) :2284-2289
[5]   Plasma interaction with microbes [J].
Laroussi, M ;
Mendis, DA ;
Rosenberg, M .
NEW JOURNAL OF PHYSICS, 2003, 5 :41.1-41.10
[6]   Sterilization of contaminated matter with an atmospheric pressure plasma [J].
Laroussi, M .
IEEE TRANSACTIONS ON PLASMA SCIENCE, 1996, 24 (03) :1188-1191
[8]  
Lerouge S, 2000, J BIOMED MATER RES, V51, P128, DOI 10.1002/(SICI)1097-4636(200007)51:1<128::AID-JBM17>3.0.CO
[9]  
2-#
[10]   Low-temperature sterilization using gas plasmas: a review of the experiments and an analysis of the inactivation mechanisms [J].
Moisan, M ;
Barbeau, J ;
Moreau, S ;
Pelletier, J ;
Tabrizian, M ;
Yahia, LH .
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2001, 226 (1-2) :1-21